Titration and treatment with auto-adjusting positive airway pressure (APAP) therapy following diagnosis of obstructive sleep apnea by home sleep apnea testing results in equivalent adherence and improvement in sleepiness compared to a polysomnography titration and continuous positive airway pressure (CPAP) treatment, reports a study in the December issue of the Journal of Clinical Sleep Medicine. The authors caution that the study group of middle-aged and older predominantly male veterans was carefully selected. A commentary on the study adds that more research is needed to determine if this paradigm is applicable to “real world” patient care settings other than the VA.