Talking Sleep – An AASM Podcast
Listen to Talking Sleep, a podcast of the American Academy of Sleep Medicine (AASM), for insightful discussions about the latest developments in the practice of clinical sleep medicine. Season five is now playing, and you can listen to the archived episodes from past seasons. Be sure to subscribe through your favorite podcast platform so you never miss a new episode.
We’d love to hear from you! Send your feedback and suggestions for Talking Sleep topics and guests to podcast@aasm.org.
Season Seven
Episode 1:
Understanding Residual AHI: What Sleep Doctors Need to Know
Welcome to Season Seven of Talking Sleep! In this episode, host Dr. Seema Khosla examines a crucial clinical question: how reliable is the residual AHI measured by PAP devices? Experts Dr. Robert Thomas, Dr. Tavi Ioachimescu, and Dr. Imran Iftikhar analyze the accuracy of PAP downloads, brand differences in measurement, and implications for patient care. Through meta-analysis findings and clinical research, they explore stable versus unstable breathing patterns and how this data influences treatment decisions. (50:56) Listen now
Episode 2:
Sleep Apnea Detection: Inside the Apple Watch Algorithm
In this episode, host Dr. Seema Khosla explores the new Apple Watch sleep apnea screening algorithm with Dr. Matt Bianchi, a research scientist from Apple’s Health Technologies team. Learn about the innovative technology that monitors sleep patterns and potentially identifies sleep apnea risk through advanced wearable device capabilities. Discover how this algorithm uses accelerometry and breathing disturbance detection to screen for potential sleep apnea, its limitations, and implications for patient care. (36:44) Listen now
Episode 3:
KPAP: Exploring a Novel PAP Therapy Approach
In this episode, host Dr. Seema Khosla explores KPAP, a groundbreaking PAP therapy innovation with Dr. David White, former AASM president, and Dr. William Noah, inventor of the V-com device. Learn about this new technology that promises to make positive airway pressure more comfortable and potentially more effective for sleep apnea patients. (44:24) Listen Now
Episode 4:
Defining Well Treated Obstructive Sleep Apnea
In this episode, host Dr. Seema Khosla tackles a critical question in sleep medicine: What defines “well-treated” obstructive sleep apnea? Joined by Dr. Barry Krakow, a pioneering sleep medicine physician, the discussion explores the nuanced approach to assessing sleep apnea treatment beyond traditional metrics. Discover insights into clinical endpoints for evaluating OSA treatment, the complex relationship between upper airway collapsibility and anxiety, and innovative strategies for patients with challenging sleep disorders. (45:44) Listen Now
Episode 5:
Too Much of a Good Thing? Benefits of Lower Pap Settings
In this episode, host Dr. Seema Khosla explores a provocative question in sleep medicine: Could high pressure PAP therapy have unexpected inflammatory effects? Joined by Dr. Sanja Jelic from Columbia University and Dr. Daniel Gottlieb from Brigham and Women’s Hospital, the discussion examines emerging research that challenges conventional wisdom about positive airway pressure (PAP) therapy. (42:11) Listen Now
Episode 6:
Tirzepatide & OSA: Implementation for Sleep Clinics
In this episode, host Dr. Seema Khosla explores a transformative development in sleep medicine: the FDA approval of tirzepatide for obstructive sleep apnea (OSA). Joined by an expert panel including Dr. Atul Malhotra, lead investigator of the SURMOUNT-OSA trial, and specialists Dr. Radhika Breaden, Dr. Jeremy McConnell, and Dr. Rafael Sepulveda-Acosta, the discussion examines how sleep clinicians can effectively incorporate this groundbreaking medication into their treatment protocols. (47:27) Listen Now
Episode 7:
Decoding Women’s Sleep Health Across the Lifespan
In this episode, Dr. Seema Khosla talks with women’s sleep expert Dr. Safia Khan about women’s unique sleep challenges. Dr. Khan is an editor for A Clinical Casebook of Sleep Disorders in Women and specializes in women’s sleep health at UT Southwestern. She explains how sleep disorders affect women differently across their lives, particularly during pregnancy and menopause, and how these transitions disrupt normal sleep patterns. (47:42) Listen Now
Episode 8:
Real World Strategies for Clinician Burnout
In this episode, Dr. Seema Khosla explores the critical issue of clinician burnout with Dr. Venktesh Ramnath, Associate Clinical Professor at UC San Diego. Moving beyond typical wellness advice, Dr. Ramnath offers practical strategies for addressing burnout at its systemic roots rather than treating it as an individual failure. (59:54) Listen Now
Episode 9:
Central Sleep Apnea: Expert Insights & Treatment Priorities
In this episode, Dr. Seema Khosla examines the complexities of central sleep apnea (CSA) with sleep medicine experts Dr. Vaishnavi Kundel, Dr. Rami N. Khayat, and Dr. Aneesa Das. The discussion moves beyond basic definitions to explore the critical limitations of home sleep apnea testing in accurately detecting CSA and when in-lab polysomnography becomes essential. (1:03:10) Listen Now
Episode 10:
Exploring the Connection Between Sleep and ADHD
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Jared Saletin, a sleep researcher investigating the complex relationship between sleep and Attention-Deficit/Hyperactivity Disorder (ADHD). (46:25) Listen Now
Episode 11:
Teledentistry
In this episode of Talking Sleep, Drs. Michelle Cantwell and Aaron Glick discuss the updated American Academy of Dental Sleep Medicine (AADSM) Standards for Practice. (56:30) Listen Now
Episode 12:
Zolpidem and the Glymphatic System
In this episode of Talking Sleep, host Dr. Seema Khosla sits down with Dr. Natalie Hauglund to discuss a groundbreaking mouse study on how the popular sleep medication zolpidem affects the brain’s natural cleaning system during sleep. (31:59) Listen Now
Episode 13:
Predicting RBD Phenoconversion via Autonomic Reflex Testing
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Luca Baldelli, a neurologist from the University of Bologna and Treasurer-Elect of the International REM Sleep Behavior Disorder Study Group, to discuss breakthrough research on predicting which RBD patients will develop neurodegenerative diseases. (36:19) Listen Now
Episode 14:
OSA and PLMD
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Gulcin Benbir, professor of neurology and sleep researcher from Turkey, and Dr. Lourdes Del Rosso, sleep physician and professor at UCSF who served on the task force for updated AASM RLS guidelines, to discuss groundbreaking research on periodic limb movements in sleep (PLMS) that persist after successful sleep apnea treatment. (38:55) Listen Now
Episode 15:
Sleep Disorders in Military Veterans
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Greg Burek, a psychiatrist and former Marine, and Dr. Dmitriy Kogan, associate professor of medicine at the Medical College of Wisconsin and program director for the sleep medicine fellowship program, to discuss the unique sleep challenges facing military veterans and first responders. (1:07:08) Listen Now
Episode 16:
ASV Algorithms & Central Sleep Apnea Management
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Imran Iftikhar and Dr. Rami Khayat to discuss groundbreaking research on adaptive servo-ventilation (ASV) and the newly released AASM clinical practice guidelines for central sleep apnea treatment. (1:00:21) Listen Now
Episode 17:
Beauty Sleep: How Skin Health and Sleep Are Connected
In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Faisal Ali, professor of dermatology at the University of Central Lancashire and consultant dermatologist specializing in Mohs micrographic and laser surgery, to explore the fascinating connections between sleep and skin health. (57:51) Listen Now
Season Six
Season Five
Season Four
Season Three
Season Two
Season One

Our Host
Seema Khosla, MD, is board certified in internal medicine, pulmonary disease, critical care medicine, and sleep medicine. She works in Fargo, North Dakota, where she is the medical director of the North Dakota Center for Sleep.
Dr. Khosla is chair of the AASM Public Awareness Advisory Committee. She previously served on the AASM Task Force on Sleep Telemedicine, which developed a position paper for the use of telemedicine for the diagnosis and treatment of sleep disorders, and chaired the AASM Consumer and Clinical Technology Committee, which developed a position statement on the use of consumer sleep technology in clinical practice. Dr. Khosla also was co-chair of the AASM Sleep Medicine Trends course.
Rate, review, and subscribe so you’ll never miss an episode! Your feedback will help guide the future of this podcast. We want to know what our listeners think so please review and rate on your podcast platform!