A request for information (NOT-RM-16-023) issued by the National Institutes of Health (NIH) Common Fund seeks comments that might be used in the development of a comprehensive research program focused on the relationship of fatigue to health.
The goals of a Mechanisms of Fatigue program would be to determine whether molecular, cellular, or imaging signatures of fatigue can be defined; if so, the program would identify molecular triggers of fatigue and determine how this condition is resolved by rest in healthy individuals. This would then provide the foundation necessary to understand why fatigue can be debilitating and/or fails to resolve in the presence of disease/disorders/aging.
Responses to the RFI will be accepted until July 28, 2016. All comments must be submitted to FatigueRFI@nih.gov.