Season 7 | Episode 4

Dr. Barry Krakow | GUEST

In this episode, host Dr. Seema Khosla tackles a critical question in sleep medicine: What defines “well-treated” obstructive sleep apnea? Joined by Dr. Barry Krakow, a pioneering sleep medicine physician, the discussion explores the nuanced approach to assessing sleep apnea treatment beyond traditional metrics.

Discover insights into clinical endpoints for evaluating OSA treatment, the complex relationship between upper airway collapsibility and anxiety, and innovative strategies for patients with challenging sleep disorders. Dr. Krakow shares his unique perspectives on PAP therapy, including approaches for patients with PTSD and the potential role of behavioral interventions.

Resources

  1. Krakow B, McIver ND, Ulibarri VA. Respiratory arousal control needed for insomnia OSA patients-authors’ reply. EClinicalMedicine. 2019 Nov 25;17:100207. DOI: 10.1016/j.eclinm.2019.11.002
  2. Krakow B, McIver ND, Ulibarri VA, Krakow J, Schrader RM. Prospective Randomized Controlled Trial on the Efficacy of Continuous Positive Airway Pressure and Adaptive Servo-Ventilation in the Treatment of Chronic Complex Insomnia. EClinicalMedicine. 2019 Aug 8;13:57-73. DOI: 10.1016/j.eclinm.2019.06.011
  3. Krakow BJ, McIver ND, Obando JJ, Ulibarri VA. Changes in insomnia severity with advanced PAP therapy in patients with posttraumatic stress symptoms and comorbid sleep apnea: a retrospective, nonrandomized controlled study. Mil Med Res. 2019 May 9;6(1):15. DOI: 10.1186/s40779-019-0204-y
  4. Krakow BJ, Obando JJ, Ulibarri VA, McIver ND. Positive airway pressure adherence and subthreshold adherence in posttraumatic stress disorder patients with comorbid sleep apnea. Patient Prefer Adherence. 2017 Nov 20;11:1923-1932. DOI: 10.2147/PPA.S148099
  5. Krakow B, Ulibarri VA, McIver ND, Yonemoto C, Tidler A, Obando J, Foley-Shea MR, Ornelas J, Dawson S. Reversal of PAP Failure With the REPAP Protocol. Respir Care. 2017 Apr;62(4):396-408. DOI: 10.4187/respcare.05032
  6. Krakow B, Krakow J, Ulibarri VA, McIver ND. Frequency and accuracy of “RERA” and “RDI” terms in the Journal of Clinical Sleep Medicine from 2006 through 2012. J Clin Sleep Med. 2014 Feb 15;10(2):121-4. DOI: 10.5664/jcsm.3432
  7. Krakow B, Melendrez D, Pedersen B, Johnston L, Hollifield M, Germain A, Koss M, Warner TD, Schrader R. Complex insomnia: insomnia and sleep-disordered breathing in a consecutive series of crime victims with nightmares and PTSD. Biol Psychiatry. 2001 Jun 1;49(11):948-53. DOI: 10.1016/s0006-3223(00)01087-8